ZFIN ID: ZDB-EXP-170703-1
Experiment Conditions Description: chemical treatment by environment: mevastatin
chemical treatment by environment: mevastatin
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: mevastatin
Synonyms: (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, antibiotic ML 236B, Compactin, CS 500, mevastatin, mevastatina, mevastatine, mevastatinum, ML 236 B, ML-236B
Definition: A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.
Ontology: Chebi [CHEBI:34848]
Publication: Wei et al., 2017