| ZFIN ID: ZDB-EXP-170703-1 |
Experiment Conditions Description: chemical treatment by environment: mevastatin
| chemical treatment by environment: mevastatin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | mevastatin |
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| Synonyms: | (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, antibiotic ML 236B, Compactin, CS 500, mevastatin, mevastatina, mevastatine, mevastatinum, ML 236 B, ML-236B |
| Definition: | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. |
| Ontology: | ChEBI [CHEBI:34848] ( EBI ) |
| Publication: | Wei et al., 2017 |
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