Search Ontology:
ChEBI

mevastatin

Term ID
CHEBI:34848
Synonyms
  • (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
  • antibiotic ML 236B
  • Compactin
  • CS 500
  • mevastatin
  • mevastatina
  • mevastatine
  • mevastatinum
  • ML 236 B
  • ML-236B
Definition
A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from mevastatin
Phenotype where environments contain mevastatin
Phenotype modified by environments containing mevastatin
Phenotype affecting mevastatin
Human Disease Model
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