ZFIN ID: ZDB-EXP-170531-2 |
Experiment Conditions Description: chemical treatment by environment: miconazole
chemical treatment by environment: miconazole |
---|
Name: | chemical treatment by environment |
---|---|
Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | miconazole |
---|---|
Synonyms: | (+-)-miconazole, (RS)-miconazole, 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole, 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole, Daktarin IV, Miconazole, Monistat IV (TN), rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, rac-miconazole |
Definition: | A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. |
Ontology: | ChEBI [CHEBI:6923] ( EBI ) |
Publication: | Yang et al., 2017 |
---|