Search Ontology:
ChEBI

miconazole

Term ID
CHEBI:6923
Synonyms
  • (+-)-miconazole
  • (RS)-miconazole
  • 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
  • 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
  • Daktarin IV
  • Miconazole
  • Monistat IV (TN)
  • rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
  • rac-miconazole
Definition
A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
References
  • cas:22916-47-8
  • drugbank:DB01110
  • kegg.drug:D00416
  • pubmed:11922774
  • pubmed:15187422
  • pubmed:15778703
  • pubmed:16608920
  • pubmed:24389479
  • pubmed:24533891
  • pubmed:24550099
  • pubmed:24629000
  • pubmed:24842191
  • pubmed:24852893
  • pubmed:24919490
  • pubmed:25070654
  • pubmed:25084742
  • pubmed:25179092
  • pubmed:8683405
  • reaxys:965511
  • wikipedia.en:Miconazole
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from miconazole
Phenotype where environments contain miconazole
Phenotype modified by environments containing miconazole
Phenotype affecting miconazole
Human Disease Model