| ZFIN ID: ZDB-EXP-170413-2 |
Experiment Conditions Description: chemical treatment by injection: fingolimod, chemical treatment by injection: polypeptide
| chemical treatment by injection: fingolimod |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | fingolimod |
|---|---|
| Synonyms: | 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, fingolimod, fingolimodum, FTY720 |
| Definition: | An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate. |
| Ontology: | ChEBI [CHEBI:63115] ( EBI ) |
| chemical treatment by injection: polypeptide |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | polypeptide |
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| Synonyms: | polipeptido, Polypeptid, Polypeptide, polypeptides |
| Definition: | A peptide containing ten or more amino acid residues. |
| Ontology: | ChEBI [CHEBI:15841] ( EBI ) |
| Publication: | Kulkarni et al., 2017 |
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