fingolimod

Term ID

CHEBI:63115

Synonyms

2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
fingolimod
fingolimodum
FTY720

Definition

An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aminodiol primary amino compound

aminodiol primary amino compound Show first 5 Terms
has_role: antineoplastic agent CB1 receptor antagonist immunosuppressive agent prodrug sphingosine-1-phosphate receptor agonist

antineoplastic agent CB1 receptor antagonist immunosuppressive agent prodrug sphingosine-1-phosphate receptor agonist Show first 5 Terms
inverse has_functional_parent: 2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol fingolimod phosphate

2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol fingolimod phosphate Show first 5 Terms
inverse is_conjugate_acid_of: fingolimod(1+)

fingolimod(1+) Show first 5 Terms
is_conjugate_base_of: fingolimod(1+)

fingolimod(1+) Show first 5 Terms

Phenotype

Phenotype resulting from fingolimod

Phenotype where environments contain fingolimod

Phenotype modified by environments containing fingolimod

Human Disease Model