| ZFIN ID: ZDB-EXP-170209-4 |
Experiment Conditions Description: chemical treatment by environment: torin 1
| chemical treatment by environment: torin 1 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | torin 1 |
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| Synonyms: | 1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one, torin1 |
| Definition: | A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties. |
| Ontology: | ChEBI [CHEBI:84327] ( EBI ) |
| Publication: | Shen et al., 2016 |
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