Search Ontology: 
        
        ChEBI
            torin 1
- Term ID
 - CHEBI:84327
 - Synonyms
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- 1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
 - torin1
 
 - Definition
 - A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.
 - References
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- LINCS:LSM-1079
 - PMID:20860370
 - PMID:24424027
 - PMID:25339775
 - Reaxys:20268275
 
 - Ontology
 - ChEBI ( EBI )
 
                
                    
                        Phenotype 
                    
                    
                
                
            
        
        
    
        
            
            
    
    
    
    
                
                    
                        Phenotype resulting from torin 1
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype where environments contain torin 1
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype modified by environments containing torin 1
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype affecting torin 1
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Human Disease Model