torin 1

Term ID

CHEBI:84327

Synonyms

1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
torin1

Definition

A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.

References

lincs.smallmolecule:LSM-1079
pubmed:20860370
pubmed:24424027
pubmed:25339775
reaxys:20268275

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from torin 1

Phenotype where environments contain torin 1

Phenotype modified by environments containing torin 1

Phenotype affecting torin 1

Human Disease Model