| ZFIN ID: ZDB-EXP-160908-26 |
Experiment Conditions Description: chemical treatment by injection: oxytocin, chemical treatment by environment: dizocilpine
| chemical treatment by injection: oxytocin |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | oxytocin |
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| Synonyms: | (1-Hemicystine)oxytocin, 1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide, 3-Isoleucine-8-leucine vasopressin, Endopituitrina, L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide, Ocytocin, Orasthin, OT, oxitocina, OXT, Oxytocin, oxytocine, oxytocinum, Pitocin, Piton S, Syntocinon |
| Definition: | A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour. |
| Ontology: | ChEBI [CHEBI:7872] ( EBI ) |
| chemical treatment by environment: dizocilpine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | dizocilpine |
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| Synonyms: | (+)-dizocilpine, (+)-MK-801, (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, dizocilpina, dizocilpine, dizocilpinum, MK 801, MK-801, MK801 |
| Definition: | An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. |
| Ontology: | ChEBI [CHEBI:34725] ( EBI ) |
| Publication: | Zimmermann et al., 2016 |
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