| ZFIN ID: ZDB-EXP-160714-3 |
Experiment Conditions Description: chemical treatment: dizocilpine
| chemical treatment: dizocilpine |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | dizocilpine |
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| Synonyms: | (+)-dizocilpine, (+)-MK-801, (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, dizocilpina, dizocilpine, dizocilpinum, MK 801, MK-801, MK801 |
| Definition: | An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. |
| Ontology: | ChEBI [CHEBI:34725] ( EBI ) |
| Publication: | Hoffman et al., 2016 |
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