ZFIN ID: ZDB-EXP-151210-2
Experiment Conditions Description: chemical treatment: dizocilpine
chemical treatment: dizocilpine
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: dizocilpine
Synonyms: (+)-dizocilpine, (+)-MK-801, (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, dizocilpina, dizocilpine, dizocilpinum, MK 801, MK-801, MK801
Definition: An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.
Ontology: Chebi [CHEBI:34725]
Publication: Bergeron et al., 2015