| ZFIN ID: ZDB-EXP-151124-1 |
Experiment Conditions Description: chemical treatment: Ro 5-3335
| chemical treatment: Ro 5-3335 |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | Ro 5-3335 |
|---|---|
| Synonyms: | 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one, CBFbeta-Runx1 inhibitor II, Ro-5-3335, Ro5-3335 |
| Definition: | A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation. |
| Ontology: | ChEBI [CHEBI:131785] ( EBI ) |
| Publication: | Bresciani et al., 2014 |
|---|