Search Ontology:
ChEBI

Ro 5-3335

Term ID
CHEBI:131785
Synonyms
  • 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • 7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one
  • CBFbeta-Runx1 inhibitor II
  • Ro-5-3335
  • Ro5-3335
Definition
A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from Ro 5-3335
Phenotype where environments contain Ro 5-3335
Phenotype modified by environments containing Ro 5-3335
Human Disease / Model Data
Citations
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