ZFIN ID: ZDB-EXP-151104-4
Experiment Conditions Description: physical alteration: caudal fin, chemical treatment: withaferin A
physical alteration: caudal fin
Name: physical alteration
Synonyms:
Definition: Experimental condition in which an anatomical structure, cell, or organ has sustained targeted physical change, usually through the use of an instrument.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000229]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
chemical treatment: withaferin A
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: withaferin A
Synonyms: (4beta,5beta,6beta,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione, 4beta,27-dihydroxy-1-oxo-5beta,6beta-epoxywitha-2,24-dienolide, Withaferin A
Definition: A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.
Ontology: ChEBI [CHEBI:69120]  ( EBI )
Publication: LeBert et al., 2015