Search Ontology:
ChEBI

withaferin A

Term ID
CHEBI:69120
Synonyms
  • (4beta,5beta,6beta,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione
  • 4beta,27-dihydroxy-1-oxo-5beta,6beta-epoxywitha-2,24-dienolide
  • Withaferin A
Definition
A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4β,5β,6β,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.
References
  • cas:5119-48-2
  • kegg.compound:C08841
  • knapsack:C00003676
  • patent:WO2010030395
  • patent:WO2010053655
  • pubmed:22098611
  • pubmed:22935676
  • pubmed:22989414
  • pubmed:23107437
  • pubmed:23129310
  • pubmed:23318585
  • pubmed:23821767
  • reaxys:6284722
  • wikipedia.en:Withaferin_A
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from withaferin A
Phenotype where environments contain withaferin A
Phenotype modified by environments containing withaferin A
Phenotype affecting withaferin A
Human Disease Model