ZFIN ID: ZDB-EXP-141211-8
Experiment Conditions Description: physical alteration: anatomical structure, chemical treatment: DAPT
physical alteration: anatomical structure
Name: physical alteration
Synonyms:
Definition: Experimental condition in which an anatomical structure, cell, or organ has sustained targeted physical change, usually through the use of an instrument.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000229]
Name: anatomical structure
Synonyms: anatomical structures
Definition: Zebrafish anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome.
Ontology: Anatomy Ontology [ZFA:0000037]
chemical treatment: DAPT
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: DAPT
Synonyms: Dapt, gamma-secretase inhibitor IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
Definition: A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. A gamma-secretase inhibitor.
Ontology: Chebi [CHEBI:86193]
Publication: Grotek et al., 2013