ZFIN ID: ZDB-EXP-100812-4
Experiment Conditions Description: chemical treatment: orantinib
chemical treatment: orantinib
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: orantinib
Synonyms: 3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid, 3-(4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl)-2-indolinone, 3-{2,4-dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, 5-((1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid, orantinib, SU 6668, SU-6668, SU6668, TSU 68
Definition: An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.
Ontology: ChEBI [CHEBI:91088]  ( EBI )
Publication: Wiens et al., 2010