| ZFIN ID: ZDB-EXP-091029-3 |
Experiment Conditions Description: chemical treatment: pepstatin A, chemical treatment: aloxistatin
| chemical treatment: pepstatin A |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | pepstatin A |
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| Synonyms: | (3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-methyl-4-[(2S)-3-methyl-2-[(2S)-3-methyl-2-(3-methylbutanamido)butanamido]butanamido]heptanamido]propanamido]-6-methylheptanoic acid, ahpatinin C, N-(3-methylbutanoyl)-L-valyl-N-[(3S,4S)-1-{[(2S)-1-{[(2S,3S)-1-carboxy-2-hydroxy-5-methylhexan-3-yl]amino}-1-oxopropan-2-yl]amino}-3-hydroxy-6-methyl-1-oxoheptan-4-yl]-L-valinamide, pepsin inhibitor S 735A, pepstatin, pepstatina, pepstatine, pepstatinum, procidin S 735A |
| Definition: | A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases. |
| Ontology: | ChEBI [CHEBI:7989] ( EBI ) |
| chemical treatment: aloxistatin |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | aloxistatin |
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| Synonyms: | aloxistatin, aloxistatina, aloxistatine, aloxistatinum, E 64d, E-64d, E64d, Ethyl (+)-(2S,3S)-2,3-epoxy-N-((S)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate, ethyl (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylate, Loxistatin |
| Definition: | An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylbutyl)-L-leucinamide. |
| Ontology: | ChEBI [CHEBI:101381] ( EBI ) |
| Publication: | He et al., 2009 |
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