Search Ontology:
ChEBI

pepstatin A

Term ID
CHEBI:7989
Synonyms
  • (3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-methyl-4-[(2S)-3-methyl-2-[(2S)-3-methyl-2-(3-methylbutanamido)butanamido]butanamido]heptanamido]propanamido]-6-methylheptanoic acid
  • ahpatinin C
  • N-(3-methylbutanoyl)-L-valyl-N-[(3S,4S)-1-{[(2S)-1-{[(2S,3S)-1-carboxy-2-hydroxy-5-methylhexan-3-yl]amino}-1-oxopropan-2-yl]amino}-3-hydroxy-6-methyl-1-oxoheptan-4-yl]-L-valinamide
  • pepsin inhibitor S 735A
  • pepstatin
  • pepstatina
  • pepstatine
  • pepstatinum
  • procidin S 735A
Definition
A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases.
References
  • cas:26305-03-3
  • kegg.compound:C00773
  • kegg.drug:D03818
  • knapsack:C00018785
  • lincs.smallmolecule:LSM-2282
  • pdb-ccd:IHN
  • pubmed:16633575
  • pubmed:16762607
  • pubmed:18675276
  • pubmed:19401235
  • pubmed:21344392
  • pubmed:22205353
  • pubmed:22384266
  • pubmed:22804908
  • pubmed:22890034
  • pubmed:26524537
  • pubmed:30408092
  • pubmed:30658511
  • pubmed:31130231
  • pubmed:31374272
  • pubmed:31718885
  • pubmed:4600212
  • pubmed:6115767
  • reaxys:2201362
  • wikipedia.en:Pepstatin
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from pepstatin A
Phenotype where environments contain pepstatin A
Phenotype modified by environments containing pepstatin A
Phenotype affecting pepstatin A
Human Disease Model