| ZFIN ID: ZDB-EXP-260729-6 |
Experiment Conditions Description: chemical treatment by environment: A-971432
| chemical treatment by environment: A-971432 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | A-971432 |
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| Synonyms: | |
| Definition: | A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC50s of .362, >10, 0.006 μM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood–brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimer’s disease or multiple sclerosis [1][2]. |
| Ontology: | ChEBI [CHEBI:746979] ( EBI ) |
| Publication: | Qian et al., 2026 |
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