Search Ontology:
ChEBI

A-971432

Term ID
CHEBI:746979
Synonyms
Definition
A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC50s of .362, >10, 0.006 μM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood–brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimer’s disease or multiple sclerosis [1][2].
References
  • cas:1240308-45-5
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from A-971432
Phenotype where environments contain A-971432
Phenotype modified by environments containing A-971432
Phenotype affecting A-971432
Human Disease Model