| ZFIN ID: ZDB-EXP-260618-6 |
Experiment Conditions Description: chemical treatment by environment: (R)-adrenaline, chemical treatment by environment: LDN-193189
| chemical treatment by environment: (R)-adrenaline |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | (R)-adrenaline |
|---|---|
| Synonyms: | (-)-(R)-epinephrine, (-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol, (-)-adrenaline, (R)-(-)-Adnephrine, (R)-(-)-Adrenaline, (R)-(-)-Epinephrine, (R)-(-)-Epirenamine, 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, Adrenalin, adrenaline, epinefrina, Epinephrin, epinephrine, epinephrinum, Epipen, Epipen JR, L-Adrenaline, levoepinephrine, Primatene |
| Definition: | The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response. |
| Ontology: | ChEBI [CHEBI:28918] ( EBI ) |
| chemical treatment by environment: LDN-193189 |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | LDN-193189 |
|---|---|
| Synonyms: | LDN 193189, LDN193189 |
| Definition: | LDN193189 is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva. |
| Ontology: | ChEBI [CHEBI:747377] ( EBI ) |
| Publication: | Huang et al., 2025 |
|---|