Search Ontology:
ChEBI

LDN-193189

Term ID
CHEBI:747377
Synonyms
  • LDN 193189
  • LDN193189
Definition
LDN193189 is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from LDN-193189
Phenotype where environments contain LDN-193189
Phenotype modified by environments containing LDN-193189
Phenotype affecting LDN-193189
Human Disease Model
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