| ZFIN ID: ZDB-EXP-260528-1 |
Experiment Conditions Description: chemical treatment by environment: LDN-193189
| chemical treatment by environment: LDN-193189 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | LDN-193189 |
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| Synonyms: | LDN 193189, LDN193189 |
| Definition: | LDN193189 is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva. |
| Ontology: | ChEBI [CHEBI:747377] ( EBI ) |
| Publication: | Xu et al., 2026 |
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