| ZFIN ID: ZDB-EXP-260512-1 |
Experiment Conditions Description: transection: caudal fin, chemical treatment by environment: SB225002
| transection: caudal fin |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment by environment: SB225002 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | SB225002 |
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| Synonyms: | 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea, N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea, PD 157695, PD-157695, PD157695, SB 225002, SB-225002 |
| Definition: | A member of the class of phenylureas that is urea in which one of the amino groups is substituted by a (2-bromophenyl)amino group while the other is substituted by a (2-hydroxy-4-nitrophenyl)amino group. It is a potent CXCR2 chemokine receptor antagonist (IC50 = 22 nM). |
| Ontology: | ChEBI [CHEBI:93074] ( EBI ) |
| Publication: | Kaveh et al., 2020 |
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