| ZFIN ID: ZDB-EXP-260226-9 |
Experiment Conditions Description: chemical treatment by environment: doxycycline, chemical treatment by environment: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
| chemical treatment by environment: doxycycline |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | doxycycline |
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| Synonyms: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 5-hydroxy-alpha-6-deoxytetracycline, 6alpha-deoxy-5-oxytetracycline, doxiciclina, Doxycyclin, doxycycline, doxycycline (anhydrous), doxycyclinum, Jenacyclin, Supracyclin, Vibramycin |
| Definition: | Tetracycline in which the 5β-hydrogen is replaced by a hydroxy group, while the 6α-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. |
| Ontology: | ChEBI [CHEBI:50845] ( EBI ) |
| chemical treatment by environment: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
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| Synonyms: | 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea, 3-(3-methyl-1,2-thiazol-5-yl)-1-(1-methylindol-5-yl)urea, N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, SB 204741, SB-204741, SB204741 |
| Definition: | A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. |
| Ontology: | ChEBI [CHEBI:140936] ( EBI ) |
| Publication: | Yang et al., 2018 |
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