doxycycline

Term ID

CHEBI:50845

Synonyms

• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• 5-hydroxy-alpha-6-deoxytetracycline
• 6alpha-deoxy-5-oxytetracycline
• doxiciclina
• Doxycyclin
• doxycycline
• doxycycline (anhydrous)
• doxycyclinum
• Jenacyclin
• Supracyclin
• Vibramycin

Definition

Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.

References

• CAS:564-25-0
• Chemspider:10469369
• DrugBank:DB00254
• Drug_Central:961
• HMDB:HMDB0014399
• KEGG:C06973
• KEGG:D07876
• KNApSAcK:C00017127
• LIPID_MAPS_instance:LMPK07000001
• MetaCyc:CPD-19256
• PDBeChem:DXT
• PMCID:PMC8464303
• PMCID:PMC8466018
• PMID:11477376
• PMID:11850258
• PMID:11891205
• PMID:1650428
• PMID:16651635
• PMID:19630297
• PMID:23698443
• PMID:24134630
• PMID:34128838
• PMID:34228348
• PMID:34318509
• PMID:34338231
• PMID:34355683
• PMID:34551605
• PMID:34577552
• Patent:US3019260
• Patent:US3200149
• Reaxys:3041790
• VSDB:1840
• Wikipedia:Doxycycline

Ontology

ChEBI  ( EBI )

Resources

CTD