| ZFIN ID: ZDB-EXP-260121-8 |
Experiment Conditions Description: bacterial treatment by injection: Mycobacterium marinum M, chemical treatment by injection: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish), chemical treatment by environment: diazoxide
| bacterial treatment by injection: Mycobacterium marinum M |
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| Name: | bacterial treatment by injection |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000230] |
| Name: | Mycobacterium marinum M |
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| Synonyms: | Mycobacterium marinum str. M, Mycobacterium marinum strain M |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:216594] |
| chemical treatment by injection: Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish) |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | Recombinant Tumor Necrosis Factor TNF alpha (Zebrafish) |
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| Synonyms: | TNF-a, TNFalpha |
| Definition: | Tumor necrosis factor alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. Protein Sequence:AAIHLTGGYN SESKTLDWRD DQDQAFSSGG LKLVNREIII PDDGIYFVYS QVSLHISCTS ELTEEQVLMS HAVMRFSESY GGKKPLFSAI RSICTQEPES ENLWYNTIYL GAAFHLREGD RLGTDTTTAL LPMVENDNGK TFFGVFGL |
| Ontology: | ChEBI [CHEBI:197439] ( EBI ) |
| chemical treatment by environment: diazoxide |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | diazoxide |
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| Synonyms: | 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Diazossido, diazoxide, diazoxido, diazoxidum, Eudemine |
| Definition: | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. |
| Ontology: | ChEBI [CHEBI:4495] ( EBI ) |
| Publication: | Roca et al., 2022 |
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