Name: |
ferrostatin-1 |
Synonyms: |
3-amino-4-cyclohexylaminobenzoic acid ethyl ester,
ethyl 3-amino-4-(cyclohexylamino)benzoate,
Fer-1,
ferrrostatin 1
|
Definition: |
An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. |
Ontology: |
ChEBI [CHEBI:173086]
(
EBI
)
|