| ZFIN ID: ZDB-EXP-241118-5 |
Experiment Conditions Description: bacterial treatment by injection: Mycobacterium marinum, chemical treatment by environment: ferrostatin-1
| bacterial treatment by injection: Mycobacterium marinum |
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| Name: | bacterial treatment by injection |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000230] |
| Name: | Mycobacterium marinum |
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| Synonyms: | Mycobacterium balnei, Mycobacterium platypoecilus |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:1781] |
| chemical treatment by environment: ferrostatin-1 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | ferrostatin-1 |
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| Synonyms: | 3-amino-4-cyclohexylaminobenzoic acid ethyl ester, ethyl 3-amino-4-(cyclohexylamino)benzoate, Fer-1, ferrrostatin 1 |
| Definition: | An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. |
| Ontology: | ChEBI [CHEBI:173086] ( EBI ) |
| Publication: | Luo et al., 2021 |
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