| ZFIN ID: ZDB-EXP-240604-4 |
Experiment Conditions Description: chemical treatment by environment: BAY 73-6691, chemical treatment by environment: gamma-hexachlorocyclohexane
| chemical treatment by environment: BAY 73-6691 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | BAY 73-6691 |
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| Synonyms: | (R)-BAY 73-6691, (R)-BAY-73-6691, 1-(2-chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one, 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, BAY 736691, BAY-73-6691, BAY736691 |
| Definition: | A member of the class of pyrazolopyrimidines that is 4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine substituted by 2-chlorophenyl, oxo, and (2R)-3,3,3-trifluoro-2-methylpropyl groups at positions 1, 4 and 6, respectively. It is a potent and selective inhibitor of phosphodiesterase 9 (PDE9), currently in pre-clinical development for the treatment of Alzheimer's disease. |
| Ontology: | ChEBI [CHEBI:231440] ( EBI ) |
| chemical treatment by environment: gamma-hexachlorocyclohexane |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | gamma-hexachlorocyclohexane |
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| Synonyms: | (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2c,3t,4c,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane, 1,2,3,4,5,6-Hexachlorocyclohexane, Benzene hexachloride, gamma-1,2,3,4,5,6-hexachlorocyclohexane, gamma-benzene hexachloride, gamma-BHC, gamma-HCH, gamma-hexachlorocyclohexane, gamma-Hexachlorzyklohexan, gamma-lindane, Kwell, Lindan, Lindane |
| Definition: | |
| Ontology: | ChEBI [CHEBI:32888] ( EBI ) |
| Publication: | Li et al., 2020 |
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