BAY 73-6691

Term ID

CHEBI:231440

Synonyms

• (R)-BAY 73-6691
• (R)-BAY-73-6691
• 1-(2-chlorophenyl)-1,5-dihydro-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-4H-pyrazolo[3,4-d]pyrimidin-4-one
• 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
• BAY 736691
• BAY-73-6691
• BAY736691

Definition

A member of the class of pyrazolopyrimidines that is 4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine substituted by 2-chlorophenyl, oxo, and (2R)-3,3,3-trifluoro-2-methylpropyl groups at positions 1, 4 and 6, respectively. It is a potent and selective inhibitor of phosphodiesterase 9 (PDE9), currently in pre-clinical development for the treatment of Alzheimer's disease.

References

• cas:794568-92-6
• pubmed:16150925
• pubmed:18674549
• pubmed:22469131
• pubmed:23034509
• pubmed:26346295
• pubmed:27071547
• pubmed:29386424
• pubmed:32826058
• pubmed:38305876
• wikipedia.en:BAY_73-6691

Ontology

ChEBI  ( EBI )