| ZFIN ID: ZDB-EXP-210130-2 |
Experiment Conditions Description: chemical treatment by environment: chloroquine, chemical treatment by environment: torin 1
| chemical treatment by environment: chloroquine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | chloroquine |
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| Synonyms: | Aralen, Artrichin, Bemaphate, Capquin, Chlorochin, chloroquine, chloroquinum, cloroquina, N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine, Nivaquine B, Resoquine, Reumachlor, Sanoquin |
| Definition: | An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. |
| Ontology: | ChEBI [CHEBI:3638] ( EBI ) |
| chemical treatment by environment: torin 1 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | torin 1 |
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| Synonyms: | 1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one, torin1 |
| Definition: | A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties. |
| Ontology: | ChEBI [CHEBI:84327] ( EBI ) |
| Publication: | Cui et al., 2012 |
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