| ZFIN ID: ZDB-EXP-201102-22 |
Experiment Conditions Description: chemical treatment by environment: abiraterone acetate, cancer xenotransplantation
| chemical treatment by environment: abiraterone acetate |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | abiraterone acetate |
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| Synonyms: | (3beta)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate, 17-(3-Pyridyl)-5,16-androstadien-3beta-acetate, 17-(pyridin-3-yl)androsta-5,16-dien-3beta-yl acetate, Zytiga |
| Definition: | A sterol ester obtained by formal condensation of the 3-hydroxy group of abiraterone with the carboxy group of acetic acid. A prodrug that is converted in vivo into abiraterone. Used for treatment of metastatic castrate-resistant prostate cancer. |
| Ontology: | ChEBI [CHEBI:68639] ( EBI ) |
| cancer xenotransplantation |
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| Name: | cancer xenotransplantation |
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| Synonyms: | |
| Definition: | Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000236] |
| Publication: | Gianoncelli et al., 2019 |
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