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ZIRC
ZFIN ID: ZDB-TGCONSTRCT-160817-1
Transgenic Construct Name: Tg(ca8:FMA-TagRFP-2A-casp8-ERT2)
Sequence Ontology ID :
Synonyms: PC-ATTAC (1), Tg(ca8:FyntagRFP-T2A-Caspase8ERT2) (1)

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Note: regulatory element of carbonic anhydrase 8 drives co-expression of FyntagRFP (membrane-targeted tagRFP) and Tamoxifen-inducible Caspase8-ERT2 linked by T2A peptide exclusively in cerebellar Purkinje neurons line allows selective ablation of cerebellar Purkinje cells by adding Tamoxifen to the rearing medium

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CONSTRUCT COMPONENTS
Regulatory Regions: ca8 (1)
Coding Sequences: TagRFP (1)
2A (1), ERT2 (1), FMA (1)
casp8 (1)
Contains: TOL2
GENOMIC FEATURES THAT UTILIZE Tg(ca8:FMA-TagRFP-2A-casp8-ERT2)
Genomic Feature Affected Genomic Regions    
bz11Tg    
TRANSGENICS THAT UTILIZE Tg(ca8:FMA-TagRFP-2A-casp8-ERT2)No data available
SEQUENCE INFORMATIONNo data available
OTHER Tg(ca8:FMA-TagRFP-2A-casp8-ERT2) TRANSGENIC CONSTRUCT PAGESNo links to external sites
CITATIONS (2)