Transgenic Construct
Tg(sox10:irf6_R84H,myl7:EGFP))
- ID
- ZDB-TGCONSTRCT-130911-4
- Name
- Tg(sox10:irf6_R84H,myl7:EGFP))
- Previous Names
-
- Tg(sox10:irf6_R84H)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:EGFP
- Contains Sequences
- Note
-
This construct expresses dominant negative R84H irf6 under the control of the sox10 promoter. Created to model human IRF6 mutations in which arginine 84 plays a crucial role in DNA binding.
Reference: Dougherty et al. (2013)
Plasmid Map
None
Genomic Features
That Utilize Tg(sox10:irf6_R84H,myl7:EGFP)) Construct
| Genomic Feature | Affected Genomic Regions |
|---|---|
| zf395Tg |
Transgenics
That Utilize Tg(sox10:irf6_R84H,myl7:EGFP)) Construct
| Fish | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|
| zf395Tg |
|
Fig. 3
from
Dougherty et al., 2013
|
Sequence Information
Other Construct Pages
None
Citations