Transgenic Construct

Tg(UAS:GCaMP1.6)

ID
ZDB-TGCONSTRCT-110912-1
Name
Tg(UAS:GCaMP1.6)
Previous Names
  • Tg(UAS:GCAMP)
  • tg(uas:gcamp1.6)
  • Tg(UAS:Gga.Mylk-cpEGFP-Rno.Calm2)
Type
engineered_plasmid
Regulatory Regions
None
Coding Sequences
[Em λ][Ex λ]
Fpbase:EGFP
Contains Sequences
Note
This construct contains the M13 fragment of the chicken Mylk gene (which contains the target sequence for calmodulin binding), fused to the N terminus of a circularly permutated form of EGFP. The C terminus of cpEGFP is fused to the rat calmodulin gene (CaM). When Ca2+ binds to CaM, the interaction between Ca2+CaMM13 induces a conformational change in cpEGFP which causes a subsequent change in fluorescence intensity.
Plasmid Map
None
Genomic Features
That Utilize Tg(UAS:GCaMP1.6) Construct
Genomic Feature Affected Genomic Regions
s1993tTg
Transgenics
That Utilize Tg(UAS:GCaMP1.6) Construct
Sequence Information
Other Construct Pages
None
Citations