Transgenic Construct

Tg1(CMV:EGFP-lmna)

ID
ZDB-TGCONSTRCT-110523-4
Name
Tg1(CMV:EGFP-lmna)
Previous Names
  • zlamin A delta37 (1)
  • zprogerin (1)
  • Tg(CMV:EGFP-lmna.1)
Type
engineered_plasmid
Regulatory Regions
None
Coding Sequences
[Em λ][Ex λ]
Fpbase:EGFP
Contains Sequences
Note
This construct is designed to produce mutated zebrafish lamin A with a deletion of 37 amino acids. This gene product is analogous to the progerin protein product of HGPS-associated point mutations in human lamin A.
Plasmid Map
None
Genomic Features
That Utilize Tg1(CMV:EGFP-lmna) Construct
Genomic Feature Affected Genomic Regions
scf1Tg
Transgenics
That Utilize Tg1(CMV:EGFP-lmna) Construct
Fish Affected Genomic Regions Phenotype Gene Expression
scf1Tg
4 figures with image from Koshimizu et al., 2011 2 figures with image from Koshimizu et al., 2011
Sequence Information
Other Construct Pages
None
Citations