TALEN

TALEN2-BX088538

ID
ZDB-TALEN-190405-2
Name
TALEN2-BX088538
Previous Names
  • mir430 cluster (1)
Targets
Target Sequence 1
5' - TCCTTAAGAAGTCAAACC - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - GCAACAGAATCTGCATAGA - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
Df(Chr4:mir430)zf3188 dre-mir-430a-2, dre-mir-430a-4, dre-mir-430a-11, dre-mir-430a-16, dre-mir-430a-18, dre-mir-430b-1, dre-mir-430b-4, dre-mir-430b-6, dre-mir-430b-9, dre-mir-430b-10, dre-mir-430b-18, mir430c-1
Expression
Gene expression in Wild Types + TALEN2-BX088538
No data available
Phenotype
Phenotype resulting from TALEN2-BX088538
No data available
Phenotype of all Fish created by or utilizing TALEN2-BX088538
Phenotype Fish Conditions Figures
midbrain hindbrain boundary neural rod en2b expression decreased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
common myeloid progenitor spi1b expression absent, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
shield decreased size, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
blood circulation arrested, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
whole organism dorsal region chrd expression decreased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
erythroid progenitor cell gata1a expression increased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
embryo development delayed, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
whole organism ago2 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE S6 from Liu et al., 2020
endoderm sox17 expression decreased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image,  FIGURE 4 with image from Liu et al., 2020
heart contraction arrested, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
blastoderm mtus1a expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions Fig. 2 with image from Kontur et al., 2020
whole organism lacks all parts of type ventricular system, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
mesoderm snai1a expression decreased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism ventral region eve1 expression increased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism ago1 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE S6 from Liu et al., 2020
brain amorphous, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
whole organism anterior-posterior axis decreased length, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
cardiac muscle cell myl7 expression mislocalised, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image,  FIGURE 4 with image from Liu et al., 2020
forebrain neural rod six3b expression decreased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
heart development disrupted, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
post-vent region increased curvature, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
mesoderm mixl1 expression decreased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism lft2 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 4 with image from Liu et al., 2020
whole organism dorsal region gsc expression decreased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism dgcr8 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE S6 from Liu et al., 2020
whole organism ago4 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE S6 from Liu et al., 2020
heart primordium nkx2.5 expression decreased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
optic vesicle pax2a expression increased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism dicer1 expression increased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE S6 from Liu et al., 2020
post-vent region blistered, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
whole organism ventral region bmp4 expression increased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
midbrain hindbrain boundary neural rod pax2a expression decreased distribution, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
cell migration to the midline involved in heart development decreased process quality, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
whole organism dead, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions text only from Liu et al., 2020
yolk protruding, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 2 with image from Liu et al., 2020
endoderm sox32 expression decreased amount, abnormal Df(Chr4:mir430)zf3188/zf3188 standard conditions FIGURE 3 with image from Liu et al., 2020
cardiac muscle cell myl7 expression position, ameliorated Df(Chr4:mir430)zf3188/zf3188 + MO2-lft2 standard conditions FIGURE 4 with image from Liu et al., 2020
endoderm sox17 expression amount, ameliorated Df(Chr4:mir430)zf3188/zf3188 + MO2-lft2 standard conditions FIGURE 4 with image from Liu et al., 2020
Citations
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