TALEN

TALEN1-gnrh3

ID

ZDB-TALEN-160831-2

Name

TALEN1-gnrh3

Previous Names

None

Target

gnrh3 (1)

Target Sequence 1

5' - TTGGAGGTCAGTCTTTGC - 3'

Target Sequence 2

5' - TTCCACCGGGAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf713	gnrh3

Expression

Gene expression in Wild Types + TALEN1-gnrh3

No data available

Phenotype

Phenotype resulting from TALEN1-gnrh3

No data available

Phenotype of all Fish created by or utilizing TALEN1-gnrh3

Phenotype	Fish	Conditions	Figures
whole organism lhb expression increased amount, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 4 from Spicer et al., 2016
preoptic area gnrh3 expression absent, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 3 from Spicer et al., 2016
whole organism cga expression increased amount, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 4 from Spicer et al., 2016
whole organism fshb expression increased amount, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 4 from Spicer et al., 2016
brain gnrh3 expression absent, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 3 from Spicer et al., 2016
whole organism lhb expression decreased amount, abnormal	gnrh3^zf713/zf713	standard conditions	Fig. 4 from Spicer et al., 2016
female organism brain pomca expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 6 from Marvel et al., 2018
male organism periventricular nucleus agrp expression decreased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 4 from Marvel et al., 2018
male organism brain pmch expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 6 from Marvel et al., 2018
brain gnrh2 expression absent, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. S3 from Marvel et al., 2018
caudal periventricular hypothalamus npvf expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 5 from Marvel et al., 2018
brain gnrh3 expression absent, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. S2, Fig. S3 from Marvel et al., 2018
male organism brain adcyap1a expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018
female organism brain agrp expression decreased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 6 from Marvel et al., 2018
male organism brain tac3a expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018
male organism brain pomca expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 6 from Marvel et al., 2018
male organism brain npvf expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2, Fig. 5 from Marvel et al., 2018
whole organism cga expression decreased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018
brain ab1-gnrh2 labeling absent, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. S2 from Marvel et al., 2018
male organism brain agrp expression decreased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 4, Fig. 6 from Marvel et al., 2018
female organism brain scg2a expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2, Fig. 3 from Marvel et al., 2018
whole organism cga expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018
female organism brain adcyap1a expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018
female organism brain npvf expression increased amount, abnormal	gnrh2^{zf3139/zf3139}; gnrh3^zf713/zf713	standard conditions	Fig. 2 from Marvel et al., 2018

Citations