TALEN

TALEN1-wwtr1

ID

ZDB-TALEN-151218-2

Name

TALEN1-wwtr1

Previous Names

None

Target

wwtr1 (1)

Target Sequence 1

5' - TGCCGCAGTCTTTCTTC - 3'

Target Sequence 2

5' - TGCCGGGAGTGGGAGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mw49	wwtr1

Expression

Gene expression in Wild Types + TALEN1-wwtr1

No data available

Phenotype

Phenotype resulting from TALEN1-wwtr1

No data available

Phenotype of all Fish created by or utilizing TALEN1-wwtr1

Phenotype	Fish	Conditions	Figures
liver and biliary system wwtr1 expression absent, abnormal	wwtr1^mw49/mw49	standard conditions	Fig. S4 from Brandt et al., 2020
retinal pigmented epithelium absent, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
retinal pigmented epithelium malformed, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
heart edematous, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
vasculature hemorrhagic, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
retinal neural layer malformed, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
retinal pigment epithelium development process quality, abnormal	wwtr1^mw49/+; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
head krt4 expression decreased amount, abnormal	wwtr1^mw49/mw49; yap1^mw48/mw48	standard conditions	Fig. 7 from Buono et al., 2021
embryo development arrested, abnormal	wwtr1^mw49/mw49; yap1^mw48/mw48	standard conditions	Fig. 1 from Miesfeld et al., 2015
head tyrp1b expression decreased amount, abnormal	wwtr1^mw49/mw49; yap1^mw48/mw48	standard conditions	Fig. 7 from Buono et al., 2021
head tyr expression decreased amount, abnormal	wwtr1^mw49/mw49; yap1^mw48/mw48	standard conditions	Fig. 7 from Buono et al., 2021
head krt8 expression decreased amount, abnormal	wwtr1^mw49/mw49; yap1^mw48/mw48	standard conditions	Fig. 7 from Buono et al., 2021

Citations