PUBLICATION

Effects of microcystin-LR and cyanobacterial crude extracts on embryo-larval development of zebrafish (Danio rerio)

Authors
Oberemm, A., Fastner, J., and Steinberg, C.E.W.
ID
ZDB-PUB-971203-4
Date
1997
Source
Water research   31(11): 2918-2921 (Journal)
Registered Authors
Oberemm, Axel
Keywords
cyanobacterial toxins; Danio rerio; fish toxicity; microcystin-LR; zebrafish
MeSH Terms
none
PubMed
none
Abstract
Eggs of zebrafish (Danio rerio) were exposed to microcystin-LR at concentrations of 0.5, 5 and 50 µg l-1 from blastula stage up to the end of embryonic development. No effects were observed during this period. After termination of exposure and transfer into microcystin-LR free water, the evaluation at the end of the larval period showed decreased survival at 5 and 50 µg l-1 microcystin-LR. Furthermore, concentrations of 0.5, 5 and 50 µg l-1 microcystin-LR retarded larval growth. Far more pronounced effects occurred following exposure with various aqueous cyanobacterial crude extracts from field samples and batch cultures: gross malformations and high mortalities during embryonic development were observed.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping