ZFIN Person: Oberemm, Axel

ZFIN ID: ZDB-PERS-970306-3

ZFIN ID: ZDB-PERS-970306-3

Oberemm, Axel

Email:	a.oberemm@bfr.bund.de
URL:	http://www.bfr.bund.de
Affiliation:
Address:	Federal Institute for Risk Assessment (BfR) Safety of Substances and Mixtures Thielalle 88-92 Berlin, 14195 Germany
Country:
Phone:	49-188-8412-3238
Fax:	49-188-8412-3264
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

born 15.8.1960 in Cologne
Study of Biology/ Zoology at the University of Cologne (1980-1988)
Ph. D. at the Free University of Berlin, Institute for Toxicology and Embryopharmacology, work on comparative evaluation of valproic acid (VPA) and selected structural analoga and EM 12 (thalidomide analogon) on embryo-larval development of amphibians (1989-1994)
1992-1998 Scientific employee at the Institute of Freshwater Ecology and Inland fisheries (IGB): ecotoxicology/ the use of a zebrafish embryotest for the assessment of chemical stressors- environmental samples from contaminated lakes and rivers and cyanotoxins, analysing and comparing effects in a range of organismic funcions, comparative studies using different species of lower vertebrates, semi-field studies using native fish species
since 1999 at BgVV/BfR: molecular toxicology, study of protein expression after xenobiotic exposure of tissues, comparison of protein expression in male and female zebrafish

PUBLICATIONS

Wright, A.D., Papendorf, O., Konig, G.M., and Oberemm, A. (2006) Effects of cyanobacterium Fischerella ambigua isolates and cell free culture media on zebrafish (Danio rerio) embryo development. Chemosphere. 65(4):604-608

Strmac, M., Oberemm, A., and Braunbeck, T. (2002) Effects of sediment eluates and extracts from differently polluted small rivers on zebrafish embryos and larvae. Journal of Fish Biology. 61(1):24-38

Oberemm, A. (2000) The use of a refined zebrafish embryo bioassay for the assessment of aquatic toxicity. Lab Anim.. 29(7):32-40

Wiegand, C., Pflugmacher, S., Oberemm, A., and Steinberg, C. (2000) Activity development of selected detoxication enzymes during the ontogenesis of the zebrafish (Danio rerio). International review of hydrobiology. 85(4):413-423

Wiegand, C., Pflugmacher, S., Oberemm, A., Meems, N., Beattie, K.A., Codd, G.A. and Steinberg, C. (1999) Uptake and effects of microcystin-LR on detoxication enzymes of early life stages of the zebra fish (Danio rerio). Environmental toxicology. 14(1):89-96

Oberemm, A., Becker, J., Codd, G., and Steinberg, C. (1999) Effects of cyanobacterial toxins and aqueous crude extracts on the development of fish and amphibians. Environmental toxicology. 14(1):77-88

Pflugmacher, S., Wiegand, C., Oberemm, A., Beattie, K.A., Krause, E., Codd, G.A., and Steinberg, C.E. (1998) Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication. Biochimica et biophysica acta. General subjects. 1425(3):527-533

Papendorf, O., König, G.M., Wright, A.D., Chorus, I., and Oberemm, A. (1997) Mueggelone, a novel inhibitor of fish development from the fresh water cyanobacterium Aphanizomenon flos-aquae. Journal of natural products. 60(12):1298-1300

Oberemm, A., Fastner, J., and Steinberg, C.E.W. (1997) Effects of microcystin-LR and cyanobacterial crude extracts on embryo-larval development of zebrafish (Danio rerio). Water research. 31(11):2918-2921

NON-ZEBRAFISH PUBLICATIONS
Oberemm A., Meckert C., Brandenburger L., Herzig A., Lindner Y., Kalenberg K., Krause E., Ittrich C., Kopp-Schneider A., Riecke K., Stahlmann R., Richter-Reichhelm H.B. and U. Gundert-Remy. Differential signatures of protein expression in marmoset liver and thymus induced by single-dose TCDD treatment. Toxicology 206(1):33-48,2005.

Luckenbach T., Kilian M., Triebskorn R. and A. Oberemm. Assessment of the developmental success of brown trout (Salmo trutta f. fario L.) embryos in two differently polluted streams in Germany. Hydrobiologia 490(1-3):53-62,2003.

Strmac M., Oberemm A. and T. Braunbeck. Effects of sediment eluates and extracts from differently polluted small rivers on zebrafish embryos and larvae. J.Fish Biol. 61(1):24-38,2002.

Duis K. and A. Oberemm. Sensitivity of early life stages of vendace, Coregonus albula, to acid pH in postmining lakes: An experimental approach. Environ Toxicol 15(3):214-224,2000

Oberemm A. and F. Kirschbaum. Valproic acid induced normal development of the central nervous system of three species of amphibians: implications for neural tube defects and alternative experimental systems. Teratog Carcinog Mutagen 12(6):251-262,1992