PUBLICATION

Heat shock protein gene expression during embryonic development of the zebrafish

Authors
Krone, P.H., Sass, J.B., and Lele, Z.
ID
ZDB-PUB-970423-4
Date
1997
Source
Cellular and molecular life sciences : CMLS   53(1): 122-129 (Review)
Registered Authors
Krone, Patrick H., Lele, Zsolt, Sass, Jennifer
Keywords
zebrafish; heat shock; myogenesis; developmental biology; hsp90; hsp70; hsp47
MeSH Terms
  • Animals
  • Gene Expression Regulation, Developmental*
  • Heat-Shock Proteins/genetics*
  • Heat-Shock Response
  • Models, Genetic
  • Zebrafish
PubMed
9117992 Full text @ Cell. Mol. Life Sci.
Abstract
Heat shock genes exhibit complex patterns of spatial and temporal regulation during embryonic development of a wide range of organisms. Our laboratory has been involved in an analysis of heat shock gene expression in the zebrafish, a model system which is now utilized extensively for the examination of early embryonic development of vertebrates. Members of the zebrafish hsp47, hsp70 and hsp90 gene families have been cloned and shown to be closely related to their counterparts in higher vertebrates. Expression of these genes has been examined using Northern blot and whole mount in situ hybridization analyses. Both the hsp47 and hsp90 genes are expressed in a highly tissue-restricted manner during normal development. The data raise a number of interesting questions regarding the function and regulation of these heat shock genes during early zebrafish development.
Genes / Markers
Figures
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Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes