Fishing for genes controlling development
- Granato, M. and Nüsslein-Volhard, C.
- Current opinion in genetics & development 6(4): 461-468 (Review)
- Registered Authors
- Granato, Michael, Nüsslein-Volhard, Christiane
- MeSH Terms
- Cell Movement
- Signal Transduction
- 8791528 Full text @ Curr. Opin. Genet. Dev.
Granato, M. and Nüsslein-Volhard, C. (1996) Fishing for genes controlling development. Current opinion in genetics & development. 6(4):461-468.
In recent years, the zebrafish has become a popular system for studying vertebrate development. Large scale mutant searches have led to the identification of >400 genes with unique functions during embryonic and larval development. A number of these genes play important roles in well studied processes, such as dorsoventral patterning of the early embryo, notochord formation and signaling, somitogenesis and neural specification. Other newly identified genes offer opportunities to investigate less well understood processes, including locomotion behavior, organogenesis, neural crest development and axonal pathfinding.
Genes / Markers
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Engineered Foreign Genes