PUBLICATION
Scalable Neuroanatomical and Behavioral Phenotyping of Radio Frequency Radiation on Young Zebrafish
- Authors
- Wu, X., Chan, Y.S., Xiang, B., Zhang, W., Luk, K.M., Cheng, S.H., Leung, Y.F., Chan, R.H.M.
- ID
- ZDB-PUB-241121-5
- Date
- 2024
- Source
- IEEE open journal of engineering in medicine and biology 6: 899989-99 (Journal)
- Registered Authors
- Cheng, Shuk Han, Leung, Yuk Fai
- Keywords
- Behavioral effects, electromagnetic exposure, high-throughput analysis, zebrafish
- MeSH Terms
- none
- PubMed
- 39564560 Full text @ IEEE Open J Eng Med Biol
Citation
Wu, X., Chan, Y.S., Xiang, B., Zhang, W., Luk, K.M., Cheng, S.H., Leung, Y.F., Chan, R.H.M. (2024) Scalable Neuroanatomical and Behavioral Phenotyping of Radio Frequency Radiation on Young Zebrafish. IEEE open journal of engineering in medicine and biology. 6:899989-99.
Abstract
Objective: In our wireless-centric world, evaluating the health effects of radio frequency electromagnetic radiation (RF-EMR) is crucial. An existing research gap pertains to the replication of real-world specific absorption rates (SAR) for RF-EMR, especially within aquatic environments. We aimed to bridge this gap using an innovative TEM cell platform to replicate realistic SAR conditions in water and assess RF-EMR's impact on neuroanatomical and behavioral changes. Results: We examined RF-EMR effects on zebrafish embryos exposed to RF-EMR during the 4-58 hours post-fertilization phase. Temporary neuroanatomical enlargements and minor behavioral shifts were observed, diminishing by day 8 post-fertilization. Conclusion: Short-term RF-EMR exposure at tested levels did not yield significant long-term effects. Nevertheless, investigating prolonged exposure remains imperative. Our study serves as a pioneering model for future investigations into the biological consequences of RF-EMR exposure, highlighting the importance of assessing its health implications in our wireless-centric world.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping