PUBLICATION
Detection of acetylcholinesterase and butyrylcholinesterase in vitro and in vivo using a new fluorescent probe
- Authors
- Tang, X., Zhang, Y., Wang, Q., Li, Z., Zhang, C.
- ID
- ZDB-PUB-240131-16
- Date
- 2024
- Source
- Chemical communications (Cambridge, England) 60(15): 2082-2085 (Journal)
- Registered Authors
- Keywords
- none
- MeSH Terms
-
- Cholinesterase Inhibitors/pharmacology
- Acetylcholinesterase*
- Animals
- Fluorescent Dyes
- Zebrafish
- Butyrylcholinesterase*
- PubMed
- 38293842 Full text @ Chem. Commun. (Camb.)
Citation
Tang, X., Zhang, Y., Wang, Q., Li, Z., Zhang, C. (2024) Detection of acetylcholinesterase and butyrylcholinesterase in vitro and in vivo using a new fluorescent probe. Chemical communications (Cambridge, England). 60(15):2082-2085.
Abstract
A new fluorescence probe OHPD that could specifically identify acetylcholinesterase/butyrylcholinesterase has been developed and successfully applied to imaging in vivo. Probe OHPD shows significant color change, high selectivity, high sensitivity, and low detection limit for the detection of cholinesterase. Moreover, the real-time imaging in situ indicated that endogenous cholinesterase was mainly present in the yolk sac of zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping