PUBLICATION
Zebrafish Reel in Phenotypic Suppressors of Autism
- Authors
- Biran, J., Levkowitz, G.
- ID
- ZDB-PUB-160219-8
- Date
- 2016
- Source
- Neuron 89: 673-675 (Review)
- Registered Authors
- Biran, Jacob, Levkowitz, Gil
- Keywords
- none
- MeSH Terms
-
- Animals
- Autistic Disorder/drug therapy*
- Estrogens/pharmacology*
- Gene Expression Regulation/drug effects*
- Gene Expression Regulation/genetics*
- Humans
- Membrane Proteins/genetics*
- Mutation/genetics*
- Nerve Tissue Proteins/genetics*
- PubMed
- 26889805 Full text @ Neuron
Citation
Biran, J., Levkowitz, G. (2016) Zebrafish Reel in Phenotypic Suppressors of Autism. Neuron. 89:673-675.
Abstract
Chemical genetics can help decipher novel pathways underlying neurodevelopmental psychiatric impairments. Hoffman et al. (2016) utilized behavioral profiling of psychoactive compounds in zebrafish and identified estrogens as suppressors of a phenotype resulting from loss of an autism risk gene.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping