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ZIRC
ZFIN ID: ZDB-PUB-160219-8
Zebrafish Reel in Phenotypic Suppressors of Autism
Biran, J., Levkowitz, G.
Date: 2016
Source: Neuron 89: 673-675 (Review)
Registered Authors: Biran, Jacob, Levkowitz, Gil
Keywords: none
MeSH Terms:
  • Animals
  • Autistic Disorder/drug therapy*
  • Estrogens/pharmacology*
  • Gene Expression Regulation/drug effects*
  • Gene Expression Regulation/genetics*
  • Humans
  • Membrane Proteins/genetics*
  • Mutation/genetics*
  • Nerve Tissue Proteins/genetics*
PubMed: 26889805 Full text @ Neuron
ABSTRACT
Chemical genetics can help decipher novel pathways underlying neurodevelopmental psychiatric impairments. Hoffman et al. (2016) utilized behavioral profiling of psychoactive compounds in zebrafish and identified estrogens as suppressors of a phenotype resulting from loss of an autism risk gene.
ADDITIONAL INFORMATIONNo data available