PUBLICATION
Discovery of therapeutic targets by phenotype-based zebrafish screens
- Authors
- Peterson, R.T.
- ID
- ZDB-PUB-140706-24
- Date
- 2004
- Source
- Drug discovery today. Technologies 1: 49-54 (Journal)
- Registered Authors
- Peterson, Randall
- Keywords
- none
- MeSH Terms
- none
- PubMed
- 24981267 Full text @ Drug Discov Today Technol
Citation
Peterson, R.T. (2004) Discovery of therapeutic targets by phenotype-based zebrafish screens. Drug discovery today. Technologies. 1:49-54.
Abstract
The easy identification of phenotypes in the transparent zebrafish embryo has enabled numerous genetic, antisense morpholino oligonucleotide, and small molecule screens. Can zebrafish screens also be used for unbiased discovery of novel drug targets?:
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping