PUBLICATION
Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles
- Authors
- Reddy, E.R., Banote, R.K., Chatti, K., Kulkarni, P., and Rajadurai, M.S.
- ID
- ZDB-PUB-120815-15
- Date
- 2012
- Source
- Chembiochem : a European journal of chemical biology 13(13): 1889-1894 (Journal)
- Registered Authors
- Chatti, Kiranam, Kulkarni, Pushkar
- Keywords
- fluorescence, guanine, nanoparticles, synthetic fluorophore, zebrafish
- MeSH Terms
-
- Animals
- Embryo, Nonmammalian/ultrastructure*
- Fluorescence
- Fluorescent Dyes/chemistry*
- Guanine/analogs & derivatives
- Humans
- Microscopy, Fluorescence/methods
- Nanoparticles/chemistry*
- Optical Imaging
- Pyrenes/chemistry
- Whole Body Imaging/methods*
- Zebrafish/embryology*
- PubMed
- 22887835 Full text @ Chembiochem
Citation
Reddy, E.R., Banote, R.K., Chatti, K., Kulkarni, P., and Rajadurai, M.S. (2012) Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles. Chembiochem : a European journal of chemical biology. 13(13):1889-1894.
Abstract
Glowing fish: Fluorescent organic nanoparticles (FONs) were prepared from pyrene-containing guanine analogues. FONs are able to penetrate into human cells and zebrafish embryos; they are nontoxic, biocompatible and were found to be specific for muscular tissues. This study demonstrates for the first time the possibility of using FONs for in vivo, whole-body, fluorescence imaging of zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping